FAM149A

Across TCGA patient cohorts, FAM149A RNA expression is significantly associated with the protein abundance of many other proteins, with 14,586 significant associations in total. GBM shows the largest number of these associations.

The most reproducible FAM149A-associated proteins across cancer lineages are TRIM2, SMG1, and SORBS2. Each is linked with FAM149A in more than 5 cancer types. Because this analysis shows association rather than direction, both FAM149A-to-partner and partner-to-FAM149A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM149A versus TRIM2 in HNSC, with a Pearson correlation of 0.26.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM149A→partner) and Y-score (partner→FAM149A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TRIM2 →	+0.747	+0.617	<.001	.006	3	6
UCEC	SMG1 →	-0.214	-1.385	.001	<.001	3	6
BRCA	SORBS2 →	+0.551	+0.616	.002	<.001	3	6
HNSC	MYEF2 →	+0.946	+0.751	<.001	<.001	3	5
UCEC	ARFGEF3 →	+0.549	+1.461	<.001	<.001	3	5
CCRCC	NRIP2_S153 →	+0.936	+0.687	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,586 associations by consensus.

FAM149A vs TRIM2 — HNSC

Explore this scatter interactively →