FAM149A

Across TCGA patient cohorts, FAM149A protein abundance is significantly associated with the RNA expression of many other genes, with 487 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible FAM149A-associated genes across cancer lineages are CCDC198, RIMS4, and JADE3. Each is linked with FAM149A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM149A-to-partner and partner-to-FAM149A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, FAM149A versus CCDC198 in LUAD, with a Pearson correlation of 0.68.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM149A→partner) and Y-score (partner→FAM149A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCDC198 →	+0.860	+1.464	.007	.006	3	1
LUAD	RIMS4 →	+1.263	+1.068	.009	.006	3	1
LUAD	JADE3 →	+1.089	+1.477	.002	.008	3	1
LUAD	KLF8 →	-0.841	-1.234	.008	<.001	3	1
LUAD	TNFSF13B →	-0.932	-1.123	<.001	.004	3	1
LUAD	TMEM59L →	+2.042	+1.672	.002	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 487 associations by consensus.

FAM149A vs CCDC198 — LUAD

Explore this scatter interactively →