FAM149A

Across TCGA cell cohorts, FAM149A mutation is significantly associated with the RNA expression of many other genes, with 188 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM149A-associated genes across cancer lineages are CCDC179, OR1E3, and FAM83C. Each is linked with FAM149A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM149A-to-partner and partner-to-FAM149A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCDC179 grouped by FAM149A-low versus FAM149A-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM149A→partner) and Y-score (partner→FAM149A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CCDC179 →	+0.030	+4.614	<.001	.004	3	1
OESOPHAGUS	OR1E3 →	+0.036	+4.906	<.001	.006	3	1
OVARY	FAM83C →	+0.154	+4.115	.001	.002	3	1
OVARY	LCE1D →	+0.030	+3.807	<.001	.009	3	1
OVARY	MS4A10 →	+0.008	+4.196	<.001	<.001	3	1
OVARY	RBMY1A1 →	+0.071	+3.807	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 188 associations by consensus.

CCDC179 by FAM149A expression — PANCREAS

Explore this box plot interactively →