FAM13B

Across TCGA patient cohorts, FAM13B mutation is significantly associated with the RNA expression of many other genes, with 3,197 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible FAM13B-associated genes across cancer lineages are RN7SL248P, RPL17-C18orf32, and CHAF1A. Each is linked with FAM13B in more than 2 cancer types. Because this analysis shows association rather than direction, both FAM13B-to-partner and partner-to-FAM13B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by FAM13B-low versus FAM13B-high in BRCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM13B→partner) and Y-score (partner→FAM13B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RN7SL248P →	+0.067	+4.786	<.001	.004	3	3
SKCM	RPL17-C18orf32 →	+0.200	+3.711	<.001	.004	3	3
UCEC	CHAF1A →	+0.719	+2.557	<.001	<.001	3	3
LUSC	LSP1P3 →	+0.344	+4.287	.004	.008	3	3
UCEC	CIDECP1 →	+0.359	+2.670	<.001	<.001	3	3
UCEC	ZNF782 →	+0.391	+2.276	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,197 associations by consensus.

RN7SL248P by FAM13B expression — BRCA

Explore this box plot interactively →