Across TCGA patient cohorts, FAM138B mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible FAM138B-associated genes across cancer lineages are MIR6817, RN7SL607P, and RN7SL785P. Each is linked with FAM138B in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM138B-to-partner and partner-to-FAM138B results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM138B→partner) and Y-score (partner→FAM138B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	MIR6817 →	+0.494	+6.064	<.001	.002	3	1
BRCA	RN7SL607P →	+0.131	+5.575	.001	.004	3	1
BRCA	RN7SL785P →	+0.146	+4.995	.004	.009	3	1
BRCA	OR6C2 →	+0.064	+5.540	<.001	.004	3	1
BRCA	OR2T3 →	+0.045	+5.540	.008	.004	3	1
BRCA	DEFB122 →	+0.127	+5.175	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

FAM138B survival (RNA) · tumor vs normal (RNA) · all FAM138B data types