FAM120A

Across TCGA cell cohorts, FAM120A mutation is significantly associated with the RNA expression of many other genes, with 422 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAM120A-associated genes across cancer lineages are C1QL2, GPR139, and DUSP21. Each is linked with FAM120A in more than 1 cancer types. Because this analysis shows association rather than direction, both FAM120A-to-partner and partner-to-FAM120A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QL2 grouped by FAM120A-low versus FAM120A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAM120A→partner) and Y-score (partner→FAM120A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	C1QL2 →	+0.012	+4.922	<.001	.009	3	2
SOFT_TISSUE	GPR139 →	+0.022	+5.369	<.001	.004	3	1
STOMACH	DUSP21 →	+0.023	+5.285	<.001	.003	3	1
SKIN	MINAR2 →	+0.013	+4.977	<.001	.007	3	1
CNS	NOBOX →	+0.018	+4.321	<.001	.009	3	1
CNS	CYLC2 →	+0.012	+4.321	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 422 associations by consensus.

C1QL2 by FAM120A expression — BLOOD_Leukemia

Explore this box plot interactively →