FA core complex associated protein 20Genealiases: C1orf86 · FP7162
Q-omics provides the consensus-scored FAAP20 profile across patient tissues and cancer cell-line models. FAAP20 expression is associated with patient survival in 25 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, FAAP20 is differentially expressed in 15, with the highest sampling consensus in HNSC. Additionally, FAAP20 RNA expression shows 18,962 significant gene co-expression associations, with the highest sampling consensus in ACC. Together, these results highlight ACC, and HNSC as cancer lineages where FAAP20 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for FAAP20 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes FAAP20 survival associations across molecular data types. FAAP20 RNA expression shows survival associations in the most cancer types (25), followed by mutation status (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible FAAP20 RNA expression–survival associations across cancer types. High FAAP20 expression shows unfavorable associations in ACC, LGG, COAD, LIHC, CESC and UCEC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for FAAP20 RNA expression.
This table summarizes FAAP20 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 15. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for FAAP20. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. FAAP20 shows lower tumor expression in KICH and higher tumor expression in HNSC, COAD, KIRC, LIHC and LUAD. The HNSC box plot shows higher FAAP20 RNA expression in tumor versus normal tissue (log2 FC = +0.926, t-test p < 0.001).
This table shows molecular features associated with FAAP20 in patient tissues and cancer cell lines. In patient samples, FAAP20 shows the broadest associations at the RNA and protein expression levels, with ACC recurring as the lineage with the largest associated feature set. In cancer cell lines, FAAP20 RNA and mutation anchors are most strongly linked to RNA-expression features, especially in CNS, while CRISPR and shRNA rows add functional-dependency signals in LARGE_INTESTINE.
