FAAP20

Across TCGA cell cohorts, FAAP20 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible FAAP20-associated genes across cancer lineages are IL12B, TBR1, and CDC20B. Each is linked with FAAP20 in more than 1 cancer types. Because this analysis shows association rather than direction, both FAAP20-to-partner and partner-to-FAAP20 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IL12B grouped by FAAP20-low versus FAAP20-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (FAAP20→partner) and Y-score (partner→FAAP20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	IL12B →	+0.069	+3.836	<.001	.003	3	1
LARGE_INTESTINE	TBR1 →	+0.047	+3.555	<.001	.003	3	1
LARGE_INTESTINE	CDC20B →	+0.093	+3.807	<.001	.001	3	1
LARGE_INTESTINE	SPEM1 →	+0.084	+3.084	<.001	.002	3	1
LARGE_INTESTINE	COX8C →	+0.107	+2.657	<.001	.007	3	1
LARGE_INTESTINE	MSH4 →	+0.335	+3.464	<.001	.004	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

IL12B by FAAP20 expression — LARGE_INTESTINE

Explore this box plot interactively →