FAAP20

Across TCGA pan-cancer cohorts, FAAP20 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated FAAP20 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where higher FAAP20 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated FAAP20 expression acts as an unfavorable survival marker.

LUSC, BRCA, and SKCM are the cancer types where FAAP20 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Median	All	0.126	0.776	<.001	36	view →
BRCA	OS	Median	All	0.296	0.925	<.001	24	view →
SKCM	OS	Median	III,IV	0.202	0.705	.006	15	view →
CESC	OS	Median	All	0.113	0.588	.009	6	view →
KIRP	OS	Median	All	0.270	0.903	.007	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
ESCA	DFS	Median	All	0.195	0.535	.042	3	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

FAAP20–LUSC (OS)

Open the LUSC breakdown →