ESPL1

Across TCGA patient cohorts, ESPL1 RNA expression is significantly associated with the RNA expression of many other genes, with 19,067 significant associations in total. ACC shows the largest number of these associations.

The most reproducible ESPL1-associated genes across cancer lineages are BRIP1, KIF23, and CENPO. Each is linked with ESPL1 in more than 33 cancer types. Because this analysis shows association rather than direction, both ESPL1-to-partner and partner-to-ESPL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ESPL1 versus BRIP1 in THYM, with a Pearson correlation of 0.94.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ESPL1→partner) and Y-score (partner→ESPL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THYM	BRIP1 →	+1.561	+1.983	<.001	<.001	3	34
ACC	KIF23 →	+1.799	+1.707	<.001	<.001	3	34
THYM	CENPO →	+1.183	+1.972	<.001	<.001	3	34
THYM	KIF11 →	+2.223	+2.009	<.001	<.001	3	34
DLBC	KIF20B →	+1.507	+1.519	<.001	<.001	3	34
DLBC	DNA2 →	+1.707	+1.648	<.001	<.001	3	34

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,067 associations by consensus.

ESPL1 vs BRIP1 — THYM

Explore this scatter interactively →