ERC2-IT1

Across TCGA patient cohorts, ERC2-IT1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,366 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ERC2-IT1-associated proteins across cancer lineages are UPP1, MIDEAS, and NEDD4L. Each is linked with ERC2-IT1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ERC2-IT1-to-partner and partner-to-ERC2-IT1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ERC2-IT1 versus UPP1 in HNSC, with a Pearson correlation of -0.23.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ERC2-IT1→partner) and Y-score (partner→ERC2-IT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	UPP1 →	-0.782	-0.492	<.001	<.001	3	3
GBM	MIDEAS →	-0.182	-0.491	.002	<.001	3	3
LSCC	NEDD4L →	+0.532	+0.518	<.001	<.001	3	3
BRCA	NFATC4 →	-0.375	-0.028	<.001	.002	3	3
GBM	PPM1H_S211 →	+0.666	+0.612	<.001	<.001	3	3
LSCC	PXN_S322 →	-0.453	-0.412	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,366 associations by consensus.

ERC2-IT1 vs UPP1 — HNSC

Explore this scatter interactively →