ERC2-IT1

Across TCGA pan-cancer cohorts, ERC2-IT1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ERC2-IT1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where ERC2-IT1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ERC2-IT1 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

LUAD and THCA are the cancer types where ERC2-IT1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ERC2-IT1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	All	+0.033	.029	1	view →
THCA	All	All	−0.015	.045	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

ERC2-IT1–LUAD

Open the LUAD breakdown →