EPB41L4B

Across TCGA patient cohorts, EPB41L4B mutation is significantly associated with the RNA expression of many other genes, with 2,875 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EPB41L4B-associated genes across cancer lineages are RAC3, NOP10, and SEC13. Each is linked with EPB41L4B in more than 2 cancer types. Because this analysis shows association rather than direction, both EPB41L4B-to-partner and partner-to-EPB41L4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RAC3 grouped by EPB41L4B-low versus EPB41L4B-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EPB41L4B→partner) and Y-score (partner→EPB41L4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RAC3 →	+0.772	+2.331	.003	.003	3	3
UCEC	NOP10 →	+0.477	+3.130	<.001	<.001	3	3
UCEC	SEC13 →	+0.361	+1.893	<.001	<.001	3	3
UCEC	H2AZ1 →	+0.591	+1.676	<.001	.001	3	3
UCEC	CIAO2B →	+0.432	+2.191	<.001	<.001	3	3
UCEC	COX8A →	+0.338	+1.914	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,875 associations by consensus.

RAC3 by EPB41L4B expression — SKCM

Explore this box plot interactively →