ENTPD3

Across TCGA patient cohorts, ENTPD3 mutation is significantly associated with the RNA expression of many other genes, with 2,332 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ENTPD3-associated genes across cancer lineages are RNA5SP418, RNA5SP422, and AURKB. Each is linked with ENTPD3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ENTPD3-to-partner and partner-to-ENTPD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP418 grouped by ENTPD3-low versus ENTPD3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ENTPD3→partner) and Y-score (partner→ENTPD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP418 →	+0.634	+1.693	<.001	.007	3	3
UCEC	RNA5SP422 →	+0.781	+1.993	<.001	.001	3	3
SKCM	AURKB →	+0.686	+3.584	.001	.002	3	2
UCEC	RCC1 →	+0.455	+3.711	.002	<.001	3	2
UCEC	DDX41 →	+0.324	+2.447	.002	.001	3	2
UCEC	TRAIP →	+0.448	+3.483	.006	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,332 associations by consensus.

RNA5SP418 by ENTPD3 expression — UCEC

Explore this box plot interactively →