ENTPD3

Across TCGA pan-cancer cohorts, ENTPD3 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ENTPD3 data layer compared with 6 for mutation status and 3 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ENTPD3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ENTPD3 expression acts as an unfavorable survival marker, although some lineages such as UCEC and BRCA show a favorable association.

STAD, UCEC, and UVM are the cancer types where ENTPD3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	OS	Quartile	III,IV	0.204	0.625	<.001	60	view →
UCEC	DFS	Tertile	All	0.784	0.573	.008	56	view →
UVM	DFS	Tertile	All	0.294	0.826	.010	35	view →
BRCA	DFS	Median	IV	0.807	0.330	.001	34	view →
COAD	OS	Median	III,IV	0.832	0.564	.003	30	view →
ACC	OS	Median	III,IV	0.318	0.878	.001	25	view →
SCLC	OS	Tertile	II,III,IV	0.219	0.538	.010	16	view →
LUSC	DFS	Quartile	All	0.831	0.700	.002	14	view →
DLBC	DFS	Median	IV	1.000	0.412	.006	14	view →
TGCT	DFS	Tertile	All	0.556	0.782	.011	12	view →
SKCM	DFS	Tertile	III,IV	0.374	0.563	.007	10	view →
KICH	OS	Quartile	II,III,IV	0.583	0.933	.026	7	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

ENTPD3–STAD (OS)

Open the STAD breakdown →