Q-omics provides the consensus-scored ENPP7P12 profile across patient tissues and cancer cell-line models. ENPP7P12 expression is associated with patient survival in 20 of 34 cancer types, with the highest sampling consensus in LAML. Among the 18 cancer types available for tumor–normal comparison, ENPP7P12 is differentially expressed in 3, with the highest sampling consensus in LUSC. Additionally, ENPP7P12 RNA expression shows 10,364 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight LAML, LUSC, and THYM as cancer lineages where ENPP7P12 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for ENPP7P12 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes ENPP7P12 survival associations across molecular data types. ENPP7P12 RNA expression shows survival associations in the most cancer types (20). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible ENPP7P12 RNA expression–survival associations across cancer types. High ENPP7P12 expression shows unfavorable associations in DLBC, UVM, KICH, MESO and UCEC, but favorable associations in LAML. The LAML Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .001). Together, the overview and detailed table identify LAML as the clearest survival context for ENPP7P12 RNA expression.
This table summarizes ENPP7P12 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 3. The strongest signals are observed in LUSC for RNA.
This table ranks reproducible tumor–normal expression differences for ENPP7P12. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. ENPP7P12 shows lower tumor expression in LUSC and COAD and higher tumor expression in CHOL. The LUSC box plot shows higher ENPP7P12 RNA expression in normal versus tumor tissue (log2 FC = −0.127, t-test p = .005).
This table shows molecular features associated with ENPP7P12 in patient tissues and cancer cell lines. In patient samples, ENPP7P12 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
