ENPP7P12

Across TCGA pan-cancer cohorts, ENPP7P12 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated ENPP7P12 data layer.

The strongest signal is observed in acute myeloid leukemia (LAML), where higher ENPP7P12 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated ENPP7P12 expression acts as an unfavorable survival marker, although some lineages such as LAML and ACC show a favorable association.

LAML, DLBC, and UVM are the cancer types where ENPP7P12 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LAML	DFS	Median	All	0.497	0.263	.001	42	view →
DLBC	OS	Tertile	II,III,IV	0.729	1.000	<.001	37	view →
UVM	OS	Tertile	All	0.720	0.891	.011	21	view →
KICH	OS	Quartile	All	0.622	0.940	.005	20	view →
MESO	DFS	Tertile	IV	0.107	0.421	<.001	18	view →
UCEC	OS	Tertile	All	0.504	0.723	.005	18	view →
READ	DFS	Quartile	All	0.382	0.657	.011	17	view →
THCA	DFS	Quartile	II,III,IV	0.712	0.891	.006	17	view →
ACC	OS	Tertile	III,IV	0.835	0.476	.009	13	view →
UCS	DFS	Median	II,III,IV	0.508	0.195	.010	12	view →
LUSC	OS	Median	IV	0.255	0.851	.021	12	view →
BLCA	DFS	Tertile	All	0.458	0.646	.010	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

ENPP7P12–LAML (DFS)

Open the LAML breakdown →