ENPP7P12

Across TCGA pan-cancer cohorts, ENPP7P12 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of ENPP7P12’s most consistent transcriptional readouts.

The strongest signal is observed in lung squamous cell carcinoma (LUSC), where ENPP7P12 RNA is repressed in tumor relative to normal tissue. In most cancer types ENPP7P12 is over-expressed in tumor, although a few such as LUSC and COAD show the opposite, repressed pattern.

LUSC, CHOL, and COAD are the cancer types where ENPP7P12 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ENPP7P12 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUSC	Male	All	−0.127	.005	4	view →
CHOL	All	All	+0.131	.047	1	view →
COAD	All	III,IV	−0.117	.019	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

ENPP7P12–LUSC

Open the LUSC breakdown →