EME2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EME2 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EME2-associated genes across cancer lineages are MIR6129, RN7SL554P, and RNU6-1261P. Each is linked with EME2 in more than 1 cancer types. Because this analysis shows association rather than direction, both EME2-to-partner and partner-to-EME2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EME2→partner) and Y-score (partner→EME2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECMIR6129 →+0.440+2.496.001.00932
CESCRN7SL554P →+0.192+5.103<.001.00832
CESCRNU6-1261P →+0.358+7.584<.001<.00132
CESCMIR5700 →+0.598+5.306<.001.00632
LUSCRPL23AP60 →+0.098+4.993<.001.00232
LUSCMTHFD2P3 →+0.210+5.110<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

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