EIF5AP3

Across TCGA patient cohorts, EIF5AP3 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,535 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible EIF5AP3-associated proteins across cancer lineages are POLR2E, VDAC2_S115, and SRRT_S136. Each is linked with EIF5AP3 in more than 3 cancer types. Because this analysis shows association rather than direction, both EIF5AP3-to-partner and partner-to-EIF5AP3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, EIF5AP3 versus POLR2E in GBM, with a Pearson correlation of 0.33.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (EIF5AP3→partner) and Y-score (partner→EIF5AP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	POLR2E →	+0.178	+0.488	.002	<.001	3	4
OV	VDAC2_S115 →	-0.785	-0.175	<.001	.004	3	3
LSCC	SRRT_S136 →	-0.421	-0.384	.004	.002	3	3
HNSC	NES_S471 →	+1.158	+0.649	.005	.001	3	3
LUAD	MLLT6_S423 →	+0.460	+0.569	<.001	<.001	3	3
LSCC	CRK_S125 →	-0.458	-0.426	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,535 associations by consensus.

EIF5AP3 vs POLR2E — GBM

Explore this scatter interactively →