EIF5AP3

Across TCGA pan-cancer cohorts, EIF5AP3 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated EIF5AP3 data layer.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher EIF5AP3 RNA is associated with better overall survival. In most high-consensus cancer types, elevated EIF5AP3 expression acts as an unfavorable survival marker, although some lineages such as BLCA and CESC show a favorable association.

BLCA, UCEC, and MESO are the cancer types where EIF5AP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	OS	Tertile	All	0.793	0.645	.001	63	view →
UCEC	DFS	Quartile	All	0.843	0.910	.001	44	view →
MESO	DFS	Median	II,III,IV	0.238	0.663	.002	36	view →
UVM	DFS	Median	III,IV	0.207	0.740	.005	32	view →
SARC	OS	Tertile	All	0.630	0.810	<.001	32	view →
ACC	DFS	Quartile	II,III,IV	0.331	0.795	.004	26	view →
THCA	OS	Quartile	IV	0.566	0.924	.005	22	view →
CESC	OS	Tertile	II,III,IV	0.700	0.427	.026	20	view →
LIHC	DFS	Tertile	All	0.448	0.599	.004	16	view →
SKCM	OS	Tertile	All	0.706	0.872	.009	13	view →
GBM	OS	Quartile	All	0.242	0.445	.006	12	view →
TGCT	DFS	Median	All	0.894	0.768	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

EIF5AP3–BLCA (OS)

Open the BLCA breakdown →