EGFEM1P

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EGFEM1P mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EGFEM1P-associated genes across cancer lineages are RNA5SP357, RNA5SP414, and MIR7976. Each is linked with EGFEM1P in more than 1 cancer types. Because this analysis shows association rather than direction, both EGFEM1P-to-partner and partner-to-EGFEM1P results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EGFEM1P→partner) and Y-score (partner→EGFEM1P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNA5SP357 →+0.887+3.881<.001.00431
UCECRNA5SP414 →+0.657+5.577.007<.00131
UCECMIR7976 →+0.970+4.453<.001<.00131
UCECCICP28 →+0.032+4.351.003<.00131
UCECMIR7856 →+1.131+3.677.005.00731
UCECRN7SL134P →+0.210+3.599.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

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