EFCAB7

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, EFCAB7 mutation is significantly associated with the RNA expression of many other genes, with 2,700 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible EFCAB7-associated genes across cancer lineages are UBE2V1P4, RNU4-58P, and PRM3. Each is linked with EFCAB7 in more than 2 cancer types. Because this analysis shows association rather than direction, both EFCAB7-to-partner and partner-to-EFCAB7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB7→partner) and Y-score (partner→EFCAB7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CESCUBE2V1P4 →+0.195+5.103<.001.00833
UCECRNU4-58P →+0.142+2.194.004.00233
SKCMPRM3 →+0.151+3.180<.001.00433
PRADRN7SL74P →+0.149+5.993.002.00232
CESCRN7SL248P →+0.212+7.584<.001<.00132
LUADOR7E97P →+0.033+5.912<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,700 associations by consensus.

Exploration