Across TCGA pan-cancer cohorts, EFCAB7 RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of EFCAB7’s most consistent transcriptional readouts.
The strongest signal is observed in kidney chromophobe (KICH), where EFCAB7 RNA is repressed in tumor relative to normal tissue. In most cancer types EFCAB7 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.
KICH, THCA, and LIHC are the cancer types where EFCAB7 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in EFCAB7 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.