EFCAB1

Across TCGA cell cohorts, EFCAB1 mutation is significantly associated with the mutation status of many other genes, with 1,626 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible EFCAB1-associated genes across cancer lineages are TXNDC11, SERPINA5, and DEPDC5. Each is linked with EFCAB1 in more than 2 cancer types. Because this analysis shows association rather than direction, both EFCAB1-to-partner and partner-to-EFCAB1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TXNDC11 grouped by EFCAB1-low versus EFCAB1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (EFCAB1→partner) and Y-score (partner→EFCAB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	TXNDC11 →	+4.321	+5.285	.005	.005	1	3
BLOOD_Leukemia	SERPINA5 →	+5.321	+5.894	.002	.002	1	3
LARGE_INTESTINE	DEPDC5 →	+2.043	+3.693	.009	.009	1	2
LARGE_INTESTINE	KIAA0930 →	+3.007	+3.584	.008	.008	1	2
LARGE_INTESTINE	STAG2 →	+2.936	+4.471	.001	.001	1	2
BLOOD_Leukemia	RBBP7 →	+4.321	+5.285	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,626 associations by consensus.

TXNDC11 by EFCAB1 expression — BLOOD_Leukemia

Explore this box plot interactively →