Q-omics provides the consensus-scored EDDM3DP profile across patient tissues and cancer cell-line models. EDDM3DP expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in OV. Among the 18 cancer types available for tumor–normal comparison, EDDM3DP is differentially expressed in 5, with the highest sampling consensus in LUAD. Additionally, EDDM3DP RNA expression shows 6,672 significant protein co-abundance associations, with the highest sampling consensus in LUAD. Together, these results highlight OV, and LUAD as cancer lineages where EDDM3DP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for EDDM3DP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes EDDM3DP survival associations across molecular data types. EDDM3DP RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible EDDM3DP RNA expression–survival associations across cancer types. High EDDM3DP expression shows unfavorable associations in OV, KIRC, LIHC and ACC, but favorable associations in LUAD and CESC. The OV Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .005). Together, the overview and detailed table identify OV as the clearest survival context for EDDM3DP RNA expression.
This table summarizes EDDM3DP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in LUAD for RNA.
This table ranks reproducible tumor–normal expression differences for EDDM3DP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. EDDM3DP shows lower tumor expression in BRCA and higher tumor expression in LUAD, BLCA, KICH and THCA. The LUAD box plot shows higher EDDM3DP RNA expression in tumor versus normal tissue (log2 FC = +0.096, t-test p = .010).
This table shows molecular features associated with EDDM3DP in patient tissues and cancer cell lines. In patient samples, EDDM3DP shows the broadest associations at the RNA and protein expression levels, with LUAD recurring as the lineage with the largest associated feature set.
