EDDM3DP

Across TCGA patient cohorts, EDDM3DP RNA expression is significantly associated with the go_rna of many other GO terms, with 6,251 significant associations in total. STAD shows the largest number of these associations.

The most reproducible EDDM3DP-associated GO terms across cancer lineages are B cell activation, Cellular response to biotic stimulus, and Toll-like receptor signaling pathway. Each is linked with EDDM3DP in more than 15 cancer types. Because this analysis shows association rather than direction, both EDDM3DP-to-partner and partner-to-EDDM3DP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell activation grouped by EDDM3DP-low versus EDDM3DP-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (EDDM3DP→partner) and Y-score (partner→EDDM3DP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	B cell activation →	+0.061	+0.063	<.001	<.001	3	16
STAD	Cellular response to biotic stimulus →	+0.056	+0.063	<.001	<.001	3	15
STAD	Toll-like receptor signaling pathway →	+0.054	+0.053	<.001	<.001	3	15
STAD	Reactive oxygen species metabolic process →	+0.057	+0.063	<.001	<.001	3	14
STAD	Positive regulation of lymphocyte differentiation →	+0.060	+0.067	<.001	<.001	3	14
STAD	Interleukin-6 production →	+0.042	+0.090	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,251 associations by consensus.

B cell activation by EDDM3DP expression — STAD

Explore this box plot interactively →