DNAJB5

Across TCGA patient cohorts, DNAJB5 mutation is significantly associated with the RNA expression of many other genes, with 2,951 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DNAJB5-associated genes across cancer lineages are RNU4-58P, RNU5E-10P, and RNA5SP415. Each is linked with DNAJB5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DNAJB5-to-partner and partner-to-DNAJB5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU4-58P grouped by DNAJB5-low versus DNAJB5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DNAJB5→partner) and Y-score (partner→DNAJB5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU4-58P →	+0.174	+2.368	.002	.004	3	2
UCEC	RNU5E-10P →	+0.514	+1.936	<.001	.002	3	2
UCEC	RNA5SP415 →	+0.459	+2.073	<.001	.005	3	2
CESC	TRGV11 →	+0.083	+3.996	.002	.005	3	2
COAD	RNA5SP288 →	+0.977	+4.173	<.001	.003	3	2
BRCA	SLC20A1P3 →	+0.043	+6.133	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,951 associations by consensus.

RNU4-58P by DNAJB5 expression — UCEC

Explore this box plot interactively →