DLGAP4

Across TCGA cell cohorts, DLGAP4 mutation is significantly associated with the RNA expression of many other genes, with 884 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible DLGAP4-associated genes across cancer lineages are CT45A7, GPR148, and ARGFX. Each is linked with DLGAP4 in more than 2 cancer types. Because this analysis shows association rather than direction, both DLGAP4-to-partner and partner-to-DLGAP4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CT45A7 grouped by DLGAP4-low versus DLGAP4-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLGAP4→partner) and Y-score (partner→DLGAP4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	CT45A7 →	+0.035	+3.362	<.001	.007	3	3
UPPER_AERODIGESTIVE_TRACT	GPR148 →	+0.047	+4.357	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	ARGFX →	+0.062	+4.357	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	PRAMEF9 →	+0.197	+4.357	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	DGKK →	+0.005	+4.357	<.001	.006	3	2
UPPER_AERODIGESTIVE_TRACT	METTL24 →	+0.045	+4.209	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 884 associations by consensus.

CT45A7 by DLGAP4 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →