DLG5

Across TCGA patient cohorts, DLG5 protein abundance is significantly associated with the RNA expression of many other genes, with 11,316 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible DLG5-associated genes across cancer lineages are IMPDH1P5, RNU6-1266P, and DLG5-AS1. Each is linked with DLG5 in more than 6 cancer types. Because this analysis shows association rather than direction, both DLG5-to-partner and partner-to-DLG5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DLG5 versus IMPDH1P5 in UCEC, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DLG5→partner) and Y-score (partner→DLG5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMPDH1P5 →	+0.953	+0.271	<.001	.001	3	7
CCRCC	RNU6-1266P →	+1.116	+0.302	<.001	.004	3	6
LSCC	DLG5-AS1 →	+0.572	+0.311	<.001	<.001	3	6
BRCA	TMEM254 →	+0.588	+0.385	.002	<.001	3	5
HNSC	LINC02576 →	-0.685	-0.283	.001	<.001	3	5
COAD	RLN2 →	-0.892	-0.435	.001	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,316 associations by consensus.

DLG5 vs IMPDH1P5 — UCEC

Explore this scatter interactively →