DHX36

Across TCGA patient cohorts, DHX36 protein abundance is significantly associated with the RNA expression of many other genes, with 16,240 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible DHX36-associated genes across cancer lineages are SGO1, TOPBP1, and TRAIP. Each is linked with DHX36 in more than 6 cancer types. Because this analysis shows association rather than direction, both DHX36-to-partner and partner-to-DHX36 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DHX36 versus SGO1 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHX36→partner) and Y-score (partner→DHX36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SGO1 →	+0.761	+0.210	<.001	.001	3	7
LSCC	TOPBP1 →	+0.876	+0.426	<.001	<.001	3	7
GBM	TRAIP →	+0.740	+0.194	<.001	.002	3	7
LSCC	SMC4 →	+0.935	+0.445	<.001	<.001	3	7
LSCC	ECT2 →	+1.029	+0.412	<.001	<.001	3	7
GBM	POLQ →	+0.974	+0.244	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,240 associations by consensus.

DHX36 vs SGO1 — GBM

Explore this scatter interactively →