DHRS7B

Across TCGA patient cohorts, DHRS7B mutation is significantly associated with the RNA expression of many other genes, with 908 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DHRS7B-associated genes across cancer lineages are USP12PY, NUTF2P8, and YTHDF3-AS1. Each is linked with DHRS7B in more than 1 cancer types. Because this analysis shows association rather than direction, both DHRS7B-to-partner and partner-to-DHRS7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP12PY grouped by DHRS7B-low versus DHRS7B-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DHRS7B→partner) and Y-score (partner→DHRS7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	USP12PY →	+0.054	+4.685	<.001	.007	3	2
UCEC	NUTF2P8 →	+0.080	+2.134	.001	.008	3	1
UCEC	YTHDF3-AS1 →	+0.464	+1.901	.007	.004	3	1
UCEC	MAGOH3P →	+0.382	+1.847	.006	.009	3	1
UCEC	COPS8P1 →	+0.087	+1.971	<.001	.004	3	1
UCEC	RPL23AP90 →	+0.239	+1.834	.007	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 908 associations by consensus.

USP12PY by DHRS7B expression — BLCA

Explore this box plot interactively →