DGKQ

Across TCGA patient cohorts, DGKQ mutation is significantly associated with the RNA expression of many other genes, with 2,092 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DGKQ-associated genes across cancer lineages are SNORD90, RN7SL228P, and MTND6P8. Each is linked with DGKQ in more than 2 cancer types. Because this analysis shows association rather than direction, both DGKQ-to-partner and partner-to-DGKQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD90 grouped by DGKQ-low versus DGKQ-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DGKQ→partner) and Y-score (partner→DGKQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	SNORD90 →	+0.539	+4.971	<.001	.002	3	3
SKCM	RN7SL228P →	+0.050	+4.186	<.001	.007	3	2
LIHC	MTND6P8 →	+0.103	+8.503	<.001	<.001	3	2
BLCA	MIR6893 →	+0.577	+5.162	<.001	.001	3	2
UCEC	SNX7 →	+0.656	+3.600	.007	.001	3	2
UCEC	CDT1 →	+0.777	+3.480	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,092 associations by consensus.

SNORD90 by DGKQ expression — BLCA

Explore this box plot interactively →