DGKQ

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DGKQ RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated DGKQ data layer compared with 2 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher DGKQ RNA is associated with better overall survival. In most high-consensus cancer types, elevated DGKQ expression acts as an unfavorable survival marker, although some lineages such as STAD and SCLC show a favorable association.

STAD, UVM, and KIRC are the cancer types where DGKQ RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianAll0.6540.502<.00158view →
UVMDFSQuartileII,III,IV0.4660.795.01531view →
KIRCDFSTertileIV0.1830.468.00729view →
HNSCDFSMedianIII,IV0.4820.720.00222view →
SCLCDFSQuartileAll0.8190.509.00619view →
THCADFSQuartileII,III,IV0.6870.973.02318view →
MESODFSQuartileIV0.1980.726.00618view →
PRADDFSMedianAll0.8430.927.00218view →
SARCOSQuartileAll0.3490.585.00311view →
LIHCDFSMedianII,III,IV0.3110.505.0067view →
ACCDFSTertileIV0.0820.503.0246view →
LUADDFSTertileIV0.6331.000.0406view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

DGKQ–STAD (OS)

Kaplan–Meier survival curve for DGKQ RNA-high vs -low samples in STAD.

Open the STAD breakdown →

Exploration