DGKQ

Across TCGA pan-cancer cohorts, DGKQ RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of DGKQ’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where DGKQ RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DGKQ is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

HNSC, LIHC, and KIRP are the cancer types where DGKQ tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DGKQ RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.961	<.001	10	view →
LIHC	Female	II,III,IV	+1.698	<.001	9	view →
KIRP	All	All	+0.444	.001	9	view →
KIRC	All	All	+0.350	<.001	9	view →
STAD	All	II,III,IV	+1.081	<.001	8	view →
BRCA	All	II,III,IV	+0.409	<.001	6	view →
CHOL	Female	All	+2.303	<.001	5	view →
KICH	All	All	−0.579	.008	3	view →
PRAD	All	All	+0.340	.002	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

DGKQ–HNSC

Open the HNSC breakdown →