DENND11

Across TCGA patient cohorts, DENND11 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,835 significant associations in total. GBM shows the largest number of these associations.

The most reproducible DENND11-associated proteins across cancer lineages are RPL7, SDF2L1, and AFDN. Each is linked with DENND11 in more than 5 cancer types. Because this analysis shows association rather than direction, both DENND11-to-partner and partner-to-DENND11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, DENND11 versus RPL7 in GBM, with a Pearson correlation of -0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (DENND11→partner) and Y-score (partner→DENND11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RPL7 →	-0.249	-0.292	.003	.001	3	5
GBM	SDF2L1 →	-0.405	-0.492	<.001	<.001	3	5
GBM	AFDN →	+0.321	+0.489	<.001	<.001	3	5
GBM	DOK3 →	-0.561	-0.395	.001	.003	3	5
GBM	EEF2 →	-0.292	-0.590	<.001	<.001	3	5
LSCC	GBF1 →	-0.147	-0.484	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,835 associations by consensus.

DENND11 vs RPL7 — GBM

Explore this scatter interactively →