DEFB119

Across TCGA cell cohorts, DEFB119 RNA expression is significantly associated with the mutation status of many other genes, with 9 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DEFB119-associated genes across cancer lineages are CCN4, CDHR2, and SEL1L3. Each is linked with DEFB119 in more than 1 cancer types. Because this analysis shows association rather than direction, both DEFB119-to-partner and partner-to-DEFB119 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCN4 grouped by DEFB119-low versus DEFB119-high in PANCREAS.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DEFB119→partner) and Y-score (partner→DEFB119) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	CCN4 →	+5.000	+0.231	.006	<.001	3	1
PANCREAS	CDHR2 →	+5.000	+0.231	.006	<.001	3	1
PANCREAS	SEL1L3 →	+5.000	+0.231	.006	<.001	3	1
BLOOD_Lymphoma	BAMBI →	+6.247	+0.156	<.001	<.001	3	1
BLOOD_Lymphoma	HMGXB4 →	+6.247	+0.156	<.001	<.001	3	1
BLOOD_Lymphoma	ACTR8 →	+6.247	+0.156	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

CCN4 by DEFB119 expression — PANCREAS

Explore this box plot interactively →