DEFB119

Across TCGA pan-cancer cohorts, DEFB119 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of DEFB119’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where DEFB119 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types DEFB119 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.

KIRC and STAD are the cancer types where DEFB119 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in DEFB119 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	II,III,IV	+0.029	.007	6	view →
STAD	All	All	−0.080	.043	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 2 strongest of 2 lineages.

DEFB119–KIRC

Open the KIRC breakdown →