DCUN1D5

Across TCGA patient cohorts, DCUN1D5 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible DCUN1D5-associated genes across cancer lineages are ASNS, BRCA2, and ERK2. Each is linked with DCUN1D5 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCUN1D5-to-partner and partner-to-DCUN1D5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASNS grouped by DCUN1D5-low versus DCUN1D5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCUN1D5→partner) and Y-score (partner→DCUN1D5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.526	+3.169	.008	.020	3	1
UCEC	BRCA2 →	-0.216	-2.992	.003	.036	3	1
UCEC	ERK2 →	+0.242	+3.169	.022	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ASNS by DCUN1D5 expression — UCEC

Explore this box plot interactively →