DCUN1D5

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, DCUN1D5 RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated DCUN1D5 data layer compared with 1 for mutation status and 4 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher DCUN1D5 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated DCUN1D5 expression acts as an unfavorable survival marker, although some lineages such as OV and READ show a favorable association.

ACC, LIHC, and UVM are the cancer types where DCUN1D5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSMedianAll0.4120.862<.001115view →
LIHCOSMedianAll0.6990.846<.00192view →
UVMDFSQuartileAll0.2990.847.00490view →
KIRPDFSTertileIII,IV0.0850.683<.00171view →
KICHOSMedianII,III,IV0.7870.975.00670view →
HNSCDFSQuartileAll0.2620.436<.00159view →
BLCAOSQuartileAll0.5450.727.00145view →
LGGOSMedianAll0.7510.869<.00142view →
LUADDFSMedianAll0.6870.836.00332view →
OVOSMedianIII,IV0.3730.264.00330view →
SKCMDFSQuartileII,III,IV0.5900.861.00430view →
PAADDFSTertileAll0.2210.484.00126view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

DCUN1D5–ACC (OS)

Kaplan–Meier survival curve for DCUN1D5 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration