DCAF10

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, DCAF10 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible DCAF10-associated genes across cancer lineages are OR2T6, KRTAP4-8, and KRTAP9-1. Each is linked with DCAF10 in more than 1 cancer types. Because this analysis shows association rather than direction, both DCAF10-to-partner and partner-to-DCAF10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2T6 grouped by DCAF10-low versus DCAF10-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DCAF10→partner) and Y-score (partner→DCAF10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaOR2T6 →+0.012+4.643<.001.00531
BLOOD_LymphomaKRTAP4-8 →+0.025+5.247<.001.00131
BLOOD_LymphomaKRTAP9-1 →+0.040+5.247<.001.00131
BLOOD_LymphomaKRTAP4-7 →+0.078+4.643<.001.00531
LARGE_INTESTINECD300H →+0.033+4.415<.001.00731
Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

OR2T6 by DCAF10 expression — BLOOD_Lymphoma

Box plot of OR2T6 in DCAF10-low vs DCAF10-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration