DBF4B

Across TCGA cell cohorts, DBF4B mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible DBF4B-associated genes across cancer lineages are OXT, AVPR1B, and MDFIC2. Each is linked with DBF4B in more than 1 cancer types. Because this analysis shows association rather than direction, both DBF4B-to-partner and partner-to-DBF4B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OXT grouped by DBF4B-low versus DBF4B-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (DBF4B→partner) and Y-score (partner→DBF4B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	OXT →	+0.063	+4.977	<.001	.007	3	1
SKIN	AVPR1B →	+0.006	+5.415	.007	.004	3	1
SKIN	MDFIC2 →	+0.155	+4.977	<.001	.007	3	1
LARGE_INTESTINE	NTSR2 →	+0.082	+3.793	<.001	.007	3	1
LARGE_INTESTINE	UTF1 →	+0.018	+4.217	<.001	.001	3	1
LARGE_INTESTINE	LYPD4 →	+0.055	+3.920	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OXT by DBF4B expression — SKIN

Explore this box plot interactively →