Q-omics provides the consensus-scored CYMP profile across patient tissues and cancer cell-line models. CYMP expression is associated with patient survival in 11 of 34 cancer types, with the highest sampling consensus in UCEC. Among the 18 cancer types available for tumor–normal comparison, CYMP is differentially expressed in 6, with the highest sampling consensus in BRCA. Additionally, CYMP RNA expression shows 8,932 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight UCEC, BRCA, and TGCT as cancer lineages where CYMP shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CYMP — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CYMP survival associations across molecular data types. CYMP RNA expression shows survival associations in the most cancer types (11). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CYMP RNA expression–survival associations across cancer types. High CYMP expression shows unfavorable associations in UCEC, STAD, DLBC and KIRC, but favorable associations in LUAD and MESO. The UCEC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify UCEC as the clearest survival context for CYMP RNA expression.
This table summarizes CYMP tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 6. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for CYMP. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CYMP shows lower tumor expression in BRCA and LUSC and higher tumor expression in COAD, PAAD, STAD and THCA. The BRCA box plot shows higher CYMP RNA expression in normal versus tumor tissue (log2 FC = −0.141, t-test p < 0.001).
This table shows molecular features associated with CYMP in patient tissues and cancer cell lines. In patient samples, CYMP shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.
