CYMP

Across TCGA pan-cancer cohorts, CYMP RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of CYMP’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where CYMP RNA is repressed in tumor relative to normal tissue. In most cancer types CYMP is over-expressed in tumor, although a few such as BRCA and LUSC show the opposite, repressed pattern.

BRCA, COAD, and LUSC are the cancer types where CYMP tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CYMP RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	All	All	−0.141	<.001	6	view →
COAD	All	All	+0.057	.027	3	view →
LUSC	Male	All	−0.055	.029	3	view →
PAAD	All	All	+1.617	.040	2	view →
STAD	All	All	+0.341	.036	2	view →
THCA	All	All	+0.011	.004	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

CYMP–BRCA

Open the BRCA breakdown →