CYMP

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CYMP mutation is significantly associated with the RNA expression of many other genes, with 1 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CYMP-associated genes across cancer lineages are USP9YP2. Each is linked with CYMP in more than 1 cancer types. Because this analysis shows association rather than direction, both CYMP-to-partner and partner-to-CYMP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP9YP2 grouped by CYMP-low versus CYMP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CYMP→partner) and Y-score (partner→CYMP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECUSP9YP2 →+0.054+8.066<.001.00731
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

USP9YP2 by CYMP expression — UCEC

Box plot of USP9YP2 in CYMP-low vs CYMP-high samples in UCEC.

Explore this box plot interactively →

Exploration