CYBA

Across TCGA patient cohorts, CYBA RNA expression is significantly associated with the protein abundance of many other proteins, with 19,805 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CYBA-associated proteins across cancer lineages are PTPN6, EVI2B, and APBB1IP. Each is linked with CYBA in more than 6 cancer types. Because this analysis shows association rather than direction, both CYBA-to-partner and partner-to-CYBA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CYBA versus PTPN6 in GBM, with a Pearson correlation of 0.83.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CYBA→partner) and Y-score (partner→CYBA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PTPN6 →	+0.767	+1.240	<.001	<.001	3	7
GBM	EVI2B →	+0.733	+0.984	<.001	<.001	3	7
GBM	APBB1IP →	+0.795	+1.257	<.001	<.001	3	7
GBM	LSP1 →	+0.730	+0.956	<.001	<.001	3	7
GBM	GPSM3 →	+0.696	+1.236	<.001	<.001	3	7
GBM	VAV1 →	+0.811	+1.285	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,805 associations by consensus.

CYBA vs PTPN6 — GBM

Explore this scatter interactively →