CXCL13

Across TCGA patient cohorts, CXCL13 mutation is significantly associated with the RNA expression of many other genes, with 2,384 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CXCL13-associated genes across cancer lineages are RPL29P32, MIR6783, and OSTCP5. Each is linked with CXCL13 in more than 1 cancer types. Because this analysis shows association rather than direction, both CXCL13-to-partner and partner-to-CXCL13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RPL29P32 grouped by CXCL13-low versus CXCL13-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CXCL13→partner) and Y-score (partner→CXCL13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	RPL29P32 →	+0.116	+6.147	<.001	.002	3	2
UCEC	MIR6783 →	+0.486	+2.002	.001	.006	3	2
SKCM	OSTCP5 →	+0.129	+3.197	.001	.005	3	1
SKCM	VN1R17P →	+0.030	+3.564	<.001	.005	3	1
SKCM	RN7SL837P →	+0.076	+4.671	<.001	.004	3	1
SKCM	RPS27P12 →	+0.110	+3.508	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,384 associations by consensus.

RPL29P32 by CXCL13 expression — BLCA

Explore this box plot interactively →