CTBP1

Across TCGA patient cohorts, CTBP1 protein abundance is significantly associated with the RNA expression of many other genes, with 17,581 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CTBP1-associated genes across cancer lineages are LCORL, HAUS3, and MXD4. Each is linked with CTBP1 in more than 7 cancer types. Because this analysis shows association rather than direction, both CTBP1-to-partner and partner-to-CTBP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CTBP1 versus LCORL in GBM, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CTBP1→partner) and Y-score (partner→CTBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LCORL →	+0.591	+0.220	<.001	<.001	3	8
LUAD	HAUS3 →	+0.430	+0.206	<.001	<.001	3	8
OV	MXD4 →	+0.639	+0.346	<.001	<.001	3	7
OV	ZNF141 →	+0.789	+0.358	<.001	.001	3	7
OV	TMEM128 →	+0.621	+0.296	<.001	<.001	3	7
OV	TMEM129 →	+0.673	+0.274	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,581 associations by consensus.

CTBP1 vs LCORL — GBM

Explore this scatter interactively →