CT45A10

Across TCGA patient cohorts, CT45A10 mutation is significantly associated with the RNA expression of many other genes, with 22 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible CT45A10-associated genes across cancer lineages are SNORD115-47, RNU7-190P, and RNU6-566P. Each is linked with CT45A10 in more than 1 cancer types. Because this analysis shows association rather than direction, both CT45A10-to-partner and partner-to-CT45A10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD115-47 grouped by CT45A10-low versus CT45A10-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CT45A10→partner) and Y-score (partner→CT45A10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SNORD115-47 →	+0.373	+7.954	<.001	.008	3	1
HNSC	RNU7-190P →	+0.482	+7.954	<.001	.008	3	1
HNSC	RNU6-566P →	+0.313	+7.954	<.001	.008	3	1
SKCM	C10orf71 →	+0.060	+4.178	.008	.002	3	1
SKCM	HTR1A →	+0.390	+3.623	<.001	.006	3	1
SKCM	RNA5SP370 →	+0.463	+4.457	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

SNORD115-47 by CT45A10 expression — HNSC

Explore this box plot interactively →