CRYZL2P

Across TCGA patient cohorts, CRYZL2P mutation is significantly associated with the RNA expression of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CRYZL2P-associated genes across cancer lineages are MUC7, RNA5SP442, and SNORD56B. Each is linked with CRYZL2P in more than 1 cancer types. Because this analysis shows association rather than direction, both CRYZL2P-to-partner and partner-to-CRYZL2P results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MUC7 grouped by CRYZL2P-low versus CRYZL2P-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CRYZL2P→partner) and Y-score (partner→CRYZL2P) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MUC7 →	+1.353	+3.855	<.001	.002	3	1
UCEC	RNA5SP442 →	+0.377	+2.766	.004	.007	3	1
UCEC	SNORD56B →	+0.596	+3.845	.001	<.001	3	1
UCEC	PINCR →	+0.297	+3.507	<.001	<.001	3	1
UCEC	IGHD4-11 →	+0.512	+4.245	<.001	.006	3	1
UCEC	LINC01809 →	+0.140	+3.136	.007	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

MUC7 by CRYZL2P expression — UCEC

Explore this box plot interactively →